SUVN-502 mesylate

CAS No. 1791396-46-7

SUVN-502 mesylate ( SUVN502 )

Catalog No. M12698 CAS No. 1791396-46-7

SUVN-502 (SUVN502)is a potent, selective, brain penetrant and orally active 5-HT6 receptor antagonist with Ki of 2.04 nM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 267 Get Quote
50MG 1062 Get Quote
100MG 1611 Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    SUVN-502 mesylate
  • Note
    Research use only, not for human use.
  • Brief Description
    SUVN-502 (SUVN502)is a potent, selective, brain penetrant and orally active 5-HT6 receptor antagonist with Ki of 2.04 nM.
  • Description
    SUVN-502 (SUVN502)is a potent, selective, brain penetrant and orally active 5-HT6 receptor antagonist with Ki of 2.04 nM; shows high selectivity over 5-HT2A receptor and other 100 target sites; produces synergistic effects in extracellular levels of acetylcholine in the ventral hippocampus combined with donepezil and memantine; shows potential for treatment of Alzheimer's disease.Alzheimer Disease Phase 2 Clinical
  • Synonyms
    SUVN502
  • Pathway
    Endocrinology/Hormones
  • Target
    5-HT Receptor
  • Recptor
    5-HT Receptor
  • Research Area
    Neurological Disease
  • Indication
    Alzheimer Disease

Chemical Information

  • CAS Number
    1791396-46-7
  • Formula Weight
    574.51
  • Molecular Formula
    C22H28BrN3O6S2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    CN1CCN(CC1)CC2=CN(C3=C2C=C(C=C3)OC)S(=O)(=O)C4=CC=CC=C4Br.CS(=O)(=O)O.CS(=O)(=O)O
  • Chemical Name
    1-((2-bromophenyl)sulfonyl)-5-methoxy-3-((4-methylpiperazin-1-yl)methyl)-1H-indole methanesulfonate

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Nirogi R, et al. J Med Chem. 2017 Mar 9;60(5):1843-1859.
2. Nirogi R, et al. J Pharm Biomed Anal. 2017 Apr 14;145:423-430.
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