SUVN-502 mesylate
CAS No. 1791396-46-7
SUVN-502 mesylate ( SUVN502 )
Catalog No. M12698 CAS No. 1791396-46-7
SUVN-502 (SUVN502)is a potent, selective, brain penetrant and orally active 5-HT6 receptor antagonist with Ki of 2.04 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
5MG | 267 | Get Quote |
|
50MG | 1062 | Get Quote |
|
100MG | 1611 | Get Quote |
|
200MG | Get Quote | Get Quote |
|
500MG | Get Quote | Get Quote |
|
1G | Get Quote | Get Quote |
|
Biological Information
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Product NameSUVN-502 mesylate
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NoteResearch use only, not for human use.
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Brief DescriptionSUVN-502 (SUVN502)is a potent, selective, brain penetrant and orally active 5-HT6 receptor antagonist with Ki of 2.04 nM.
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DescriptionSUVN-502 (SUVN502)is a potent, selective, brain penetrant and orally active 5-HT6 receptor antagonist with Ki of 2.04 nM; shows high selectivity over 5-HT2A receptor and other 100 target sites; produces synergistic effects in extracellular levels of acetylcholine in the ventral hippocampus combined with donepezil and memantine; shows potential for treatment of Alzheimer's disease.Alzheimer Disease Phase 2 Clinical
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SynonymsSUVN502
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PathwayEndocrinology/Hormones
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Target5-HT Receptor
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Recptor5-HT Receptor
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Research AreaNeurological Disease
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IndicationAlzheimer Disease
Chemical Information
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CAS Number1791396-46-7
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Formula Weight574.51
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Molecular FormulaC22H28BrN3O6S2
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Purity>98% (HPLC)
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Solubility——
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SMILESCN1CCN(CC1)CC2=CN(C3=C2C=C(C=C3)OC)S(=O)(=O)C4=CC=CC=C4Br.CS(=O)(=O)O.CS(=O)(=O)O
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Chemical Name1-((2-bromophenyl)sulfonyl)-5-methoxy-3-((4-methylpiperazin-1-yl)methyl)-1H-indole methanesulfonate
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Nirogi R, et al. J Med Chem. 2017 Mar 9;60(5):1843-1859.
2. Nirogi R, et al. J Pharm Biomed Anal. 2017 Apr 14;145:423-430.
2. Nirogi R, et al. J Pharm Biomed Anal. 2017 Apr 14;145:423-430.
molnova catalog
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